et al; Eurotherm3235 Trial Collaborators. Calculation was done using both R (MatchIt) and SAS for optimal bipartite matching.  SM, Grossestreuer  GL,  RO, Chamberlain Hypothermic treatment in patients older than 65 years who are admitted due to asystole may be at risk of harm from this treatment (Our study did not reveal a significant benefit in neurological outcomes from therapeutic treatment.

 AM, eds; Committee on the Treatment of Cardiac Arrest: Current Status and Future Directions; Board on Health Sciences Policy; Institute of Medicine.  et al; International Liaison Committee on Resuscitation; American Heart Association; European Resuscitation Council; Australian Resuscitation Council; New Zealand Resuscitation Council; Heart and Stroke Foundation of Canada; InterAmerican Heart Foundation; Resuscitation Councils of Southern Africa; ILCOR Task Force on Cardiac Arrest and Cardiopulmonary Resuscitation Outcomes.

 YM, Yim We randomly selected a group of 35 patients who were not treated with hypothermia, matched by a demographic propensity score, to serve as a control group (Considerations in calculating the sample size were based on several key points: incidence of OHCA, primary outcome, and efficacy of therapeutic hypothermia.  M.  Assessment of outcome after severe brain damage.
 GE.

Using propensity matching, induced hypothermia was associated with a relative 12% reduction survival to hospital discharge, as compared with usual care (27.4% versus 29.2%, P=0.01).  JP, Larkin  GJ, Stark  et al; American Heart Association Get with the Guidelines–Resuscitation Investigators. Targeted temperature management at 33°C versus 36°C after cardiac arrest.  JP,

 MW, Salciccioli Fifteen years later, this technique was resumed focusing on a modest cooling of 32–34°C. 190 patients were eligible for study and were divided into two groups based on therapeutic approach.  et al. 18 CA is a devastating condition and associated with a mortality of more than 90%. Normand

 BG, Abella  PJ, Sinclair Is hypothermia in the victim of major trauma protective or harmful?  MW, Fink  D, Hazinski
 BS, Gaieski These observational findings warrant a randomized clinical trial to assess efficacy of therapeutic hypothermia for in-hospital cardiac arrest.Table 1.  SS, Damon a randomized, prospective study.